Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella
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چکیده
منابع مشابه
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella
To analyze the function of ciliary polycystic kidney disease 2 (PKD2) and its relationship to intraflagellar transport (IFT), we cloned the gene encoding Chlamydomonas reinhardtii PKD2 (CrPKD2), a protein with the characteristics of PKD2 family members. Three forms of this protein (210, 120, and 90 kD) were detected in whole cells; the two smaller forms are cleavage products of the 210-kD prote...
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Five paralyzed flagella mutants of Chlamydomonas reinhardtii have been isolated and characterized ultrastructurally as specifically defective for either the outer row or inner row of arms on the axonemal doublet microtubules. Four mutants falling in two genetic loci (pf-13, pf-ItA, pf-22, and pf-22A) show quantitative deficiencies for outer arms. One mutant for a third locus, pf-23, is deficien...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2007
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200704069